PI
dosing and administration
PI
infusion rate chart
PI
infusion rate calculator
Tab Number 4
Tab Number 5
- The initial infusion rate should be maintained for 30 minutes. Following the initial infusion, and if tolerated, the infusion rate may be gradually increased every 15-30 minutes, as tolerated, to the maximum infusion rate of 14 mg/kg/min (0.14 mL/kg/min)1†
- PANZYGA should be started at 1 mg/kg/min and continued at the infusion rates stated here, if tolerated1
- The example shown above illustrates a ramp-up schedule for an 80-kg patient with PI following a ramp-up of 1, 4, 8, and 14 mg/kg/min
- For patients at risk of renal dysfunction or thromboembolic events, administer PANZYGA at the minimum infusion rate practicable. Do not exceed 3.3 mg/kg/min (0.033 mL/kg/min). Discontinue if renal function deteriorates1
- 300 mg/kg to 600 mg/kg of body weight (3-6 mL/kg) administered every 3 to 4 weeks1
- The initial infusion rate should be maintained for 30 minutes. Following the initial infusion, and if tolerated, the infusion rate may be gradually increased every 15 to 30 minutes, as tolerated, to a maximum of 14 mg/kg/min (0.14 mL/kg/min)1
- infusion ramp-up rate to program into an IV infusion pump
- estimated time to complete the infusion
Adult patient with CIDP
One field from each section below is required.
Adult patient with CIDP
Based on patient’s body weight of {{weight}} and a dose of {{dose}} of PANZYGA, see below for recommended ramp-up infusion rates.
0.01 mL/kg/min
(1 mg/kg/min)
mL/hr
(if previous is tolerated)
0.02 mL/kg/min
(2 mg/kg/min)
mL/hr
(if previous is tolerated)
0.04 mL/kg/min
(4 mg/kg/min)
mL/hr
(if previous is tolerated)
0.08 mL/kg/min
(8 mg/kg/min)
mL/hr
(if previous is tolerated)
0.12 mL/kg/min
(12 mg/kg/min)
mL/hr
(if the rates above are tolerated by the patient)
Patient 2 years or older with PI
One field from each section below is required.
Patient 2 years or older with PI
Based on patient’s body weight of {{weight}} and a dose of {{dose}} of PANZYGA, see below for recommended ramp-up infusion rates.
0.01 mL/kg/min
(1 mg/kg/min)
mL/hr
(if previous is tolerated)
0.04 mL/kg/min
(4 mg/kg/min)
mL/hr
(if previous is tolerated)
0.08 mL/kg/min
(8 mg/kg/min)
mL/hr
(if previous is tolerated)
0.14 mL/kg/min
(14 mg/kg/min)
mL/hr
(if the rates above are tolerated by the patient)
Adult patient with cITP
One field from each section below is required.
Enter patient’s body weight
Adult patient with cITP
Based on patient’s body weight of {{weight}} and a dose of {{dose}} of PANZYGA, see below for recommended ramp-up infusion rates.
0.01 mL/kg/min
(1 mg/kg/min)
mL/hr
(if previous is tolerated)
0.04 mL/kg/min
(4 mg/kg/min)
mL/hr
(if previous is tolerated)
0.08 mL/kg/min
(8 mg/kg/min)
mL/hr
(if the rates above are tolerated by the patient)
